Harrison.Ai CEO Says Radiologists Need Evidence, Not AI Hype

By Arunima Rajan

In an interview with Arunima Rajan, Harrison.ai CEO and Co-founder Dr Aengus Tran says the company customised a draft reporting product for Manipal Hospitals after clinicians flagged the time spent writing long radiology reports as a key workflow challenge. 

Most AI companies in healthcare started by picking one narrow problem, getting really good at it, and then slowly expanding. You did the opposite. You trained a single model to read over a hundred findings on a chest X-ray right from the start. Walk me through that early decision. Was there a moment when someone on the team said this is too ambitious, and what made you push forward anyway?

There were many moments. And it's not wrong, it's just not what we believed would actually solve the problem. The insight came from thinking about how radiology actually works. A radiologist doesn't look at a chest X-ray and think "I'm only checking for pneumonia today." They're scanning the entire image, lungs, heart, bones, soft tissue all simultaneously.  

If we built an AI that only flagged one or two findings, we wouldn't have built a second pair of eyes. We would have been building a very expensive highlighter or a spell checker for one thing, while the radiologist still had to do all the cognitive work for everything else. That's not a workflow improvement. That's a workflow interruption.  
 
So the question became: what would it actually take to build something comprehensive? And the answer was uncomfortable, it would take an enormous amount of data, annotated at a level of quality that didn't really exist yet, and it would take time. The narrow approach made sense for companies trying to get to a demo quickly. We were trying to build something that would still be relevant in 20 years. 

You had around 145 consultant radiologists manually annotating nearly 800,000 chest X-ray studies to train this model. That is an extraordinary amount of human labor to pour into a machine learning product. Most AI founders I talk to are obsessed with reducing human involvement. You seem to have leaned into it. Why?

We're building a system that we want to reach the benchmark of a consultant radiologist, who has spent over a decade training their eyes. If you want to teach a model to see what a consultant radiologist sees, you need to show it what a consultant radiologist sees. We know inter-reader variability is real in radiology. The quality of the label is the ceiling of the model's performance. 
 
A lot of early medical AI was trained on radiology reports, the text that radiologists write after reading a scan. That's a proxy. Reports are written for clinical communication, not for training AI. They're incomplete, inconsistent, and they don't capture the spatial reasoning that makes radiology what it is. We needed radiologists to look at images and mark findings directly. That's a fundamentally different and much more expensive data collection process. 

The irony is that this investment in human expertise is what makes the AI trustworthy to humans. When a radiologist asks, "how was this trained?" and we can say "by 145+ board-certified radiologists, triple-labeled, at this scale", that's a conversation that builds confidence.  

Here is something I find fascinating about your market. You are selling a product to radiologists that essentially tells them they might be missing things. That is a delicate message to deliver to a highly trained specialist. How did you figure out the right way to position that, and did you get it wrong before you got it right?

The shift happened when we started listening more carefully to what radiologists actually worried about. It was "I'm worried about the volume. I'm worried about the pace. I'm worried about the conditions I'm working in."  

India has 1 radiologist for every 100,000 people. The UK is facing a 40% radiologist shortage. Australia is facing backlog issues. This is a global problem. You're not missing things because you're not skilled, you're missing things because you're exhausted and don’t have the capacity to accommodate all the scans.  

Every radiologist already knows the value of a colleague double-checking a difficult case. We're making that colleague available on every single read, at 3am, in a rural hospital in Tenkasi with one radiologist on call. That's not a threat to expertise. That's an extension of it. 
 
We are also transparent about what our AI doesn't do well. Radiologists respect intellectual honesty. If you oversell and they find an edge case where the model underperforms, you've lost them. If you're upfront about limitations and show them the evidence, they engage as partners.  

You are now in over a thousand sites across multiple countries, each with different regulatory regimes, different clinical workflows, different levels of infrastructure. When you are sitting in a hospital in rural India versus a tertiary care center in Australia, is it even the same product doing the same job, or does the context change what the AI means to the people using it?

It's the same model doing the same job, but the context it operates in is radically different and we had to build for that from the start. The 125 findings our CXR model looks for on a chest X-ray are the same whether you're in Hong Kong or rural Queensland or Delhi.3 But the way it integrates, the way it surfaces findings, the way it fits into whatever workflow exists would be different. That being said we have had to create products for specific markets. A good example would be our draft reporting product that we developed and customised for Manipal Hospitals. We listened to clinicians and their major concern was time consumed in writing long reports, so we developed a product to make it easier for Indian radiologists.  
The regulatory piece is complex. We have FDA 510(k) clearances in the US, CE Mark in Europe, ARTG in Australia, MHRA registered in the UK, CDCSO in India and clearances across 40+ countries.

When your AI catches something a radiologist missed and that finding changes a patient's outcome, who gets the credit? And more importantly, when something goes wrong, who carries the liability? How far along is that conversation really?

This is one of the most important conversations happening in medicine right now, and I want to be honest: it's not fully resolved. The legal and ethical frameworks are still catching up to the technology. 
 
Our AI is a decision-support tool, it surfaces findings, it flags priorities, it provides a second read. But the radiologist reviews that output, applies their clinical judgment, and signs the report. The radiologist remains the responsible clinician. 
 
What we are focused on is making sure the conversation about liability doesn't slow down adoption in ways that harm patients. The risk of not deploying AI, missed diagnoses, delayed treatment, is real and quantifiable. We need legal and regulatory frameworks to catch up, and we're actively engaged in those conversations. 

A lot of your competitors raised huge rounds, made big promises, and then struggled to get past the pilot phase. You seem to have taken a quieter path to a thousand sites. What did you understand about hospital procurement and clinical adoption that the louder players in the space got wrong?

Many AI radiology companies never scaled beyond pilot programs, not because the technology failed, but because they underestimated the human and institutional complexity of clinical adoption. 

Our products are built by clinicians, for clinicians. Involving clinical expertise from the outset ensures a more intuitive user experience and ultimately drives adoption.  Hospitals don’t buy technology, they adopt workflows. A pilot that demonstrates strong accuracy in a controlled setting doesn’t automatically translate into real-world clinical use. 

Another common misconception is around who the true customer is. Many AI companies focused on selling to administrators and IT teams, the stakeholders who can approve budgets and sign contracts. But actual adoption is determined by clinicians. If radiologists don’t trust the tool, don’t find it useful, or feel it adds friction to their workflow, the product simply won’t be used, regardless of the contract. 

Finally, our award-winning Viewer UX/UI is designed to present clinical findings clearly and intuitively. With minimal clicks and a streamlined interface, it accelerates workflows addressing a key pain point seen in many other solutions on the market. 

When you look at the broader imaging landscape, where do you see the same kind of gap between what AI can do and what clinicians actually need, and how do you decide when the technology is ready versus when you are just chasing a bigger market?

CT Brain was the natural next step. Non-contrast brain CT is one of the highest stakes read in emergency medicine, strokes, bleeds and trauma. The time-sensitivity is extreme. A patient presenting with stroke symptoms needs a read in minutes, not hours. And yet the same shortage problem that affects chest X-ray affects neuroradiology. We built a model covering 130 findings on non-contrast CT brain scans. 

Our CT Chest solution is our latest solution and is designed to work across both contrast and non-contrast scans. It can detect over 200 features including those relevant for lung cancer screening. This is where I believe the impact can be especially significant. Lung cancer remains the leading cause of cancer-related deaths globally, and the evidence supporting low-dose CT screening is strong. 

If you zoom out ten years from now, what does a radiology department look like in a world where AI like yours is standard? Are we talking about fewer radiologists doing different work, or more scans being read with the same number of people, or something that none of us are imagining yet?

I would think more radiologists doing more important work, reading more scans than we can currently imagine and reaching patients who today have no access to specialist diagnosis at all. 
 
The second thing I'd say is that the nature of the work changes. Right now, a significant portion of a radiologist's day is spent on routine reads, normal studies, common findings and straightforward cases. What AI doesn't handle well is the genuinely ambiguous case, the rare presentation, the clinical context that requires a conversation with the referring physician, the judgment call that requires experience and intuition. If AI absorbs the routine, radiologists get to spend more of their time on the cases that actually need them.  

Why Manipal Chose Harrison.ai: Dr. Sudarshan Rawat on Building a Clinical Co-Pilot for Radiology

In an interview with Arunima Rajan, Dr. Sudarshan Rawat, Head of Department, Manipal Hospitals says that modern hospital imaging department is transforming from a clinical workspace into an always-on digital environment.

For readers who may not be familiar with what's happening inside hospital imaging departments right now, can you paint the picture? What does a typical day look like for a radiologist at a large health system like Manipal, and why is the workload becoming unsustainable?
The modern hospital imaging department is transforming from a clinical workspace into an always-on digital environment. Radiologists are managing a large volume of studies and data, driven by increased reliance on imaging for nearly every diagnosis, and that requires intense mental focus for interpreting images.

Modern scanners produce higher resolution images, meaning the complexity and data required per study has risen dramatically, not just the number of studies.

A significant portion of the day of a radiologist is spent analyzing thousands of images of CT or MRI scans, dictate reports using voice recognition software, requiring constant self-editing, with communication of "critical findings” to treating clinicians. Radiologists may split time between routine reporting, subspecialty consulting, and, in some cases, performing image-guided interventional procedures.

Work is often interrupted by phone calls from emergency /ICU for urgent cases, clinicians dropping in for discussion, and technologists asking for guidance. Across the industry, we see radiologists report burnout.

That pressure is exactly why so many hospitals have started experimenting with AI. But a lot of early adopters picked tools that could only flag one or two conditions, and many of those tools ended up gathering dust. Manipal went a different route. What did you see in those early experiments across the industry that made you hold out for something more comprehensive?
Early AI deployments across the industry were too narrow and focused on single conditions, which limited their clinical value and led to poor adoption. At Manipal, we chose to wait for a more comprehensive, horizontally scalable AI approach. Our collaboration focuses on integrating AI into the clinical workflow, leveraging real-time, structured data, and supporting multiple use cases across the platform.

Once you settled on Harrison.ai’s chest X-ray AI solution, how did the actual rollout work? A chest X-ray is one of the most common and most interpretation-dependent scans in medicine. What does it look like when AI enters that workflow for the first time, and how did your radiologists react?

Once we decided on Harrison.ai’s chest X-ray solution, the rollout was designed as a seamless augmentation of the radiologist’s workflow, not a separate tool. We worked on the following steps;
  • Direct PACS/RIS integration: AI outputs appear within the existing reporting screen—no additional steps.

  • Real-time analysis: Findings are generated within seconds, including localization across a wide range of abnormalities.

  • Intelligent Clinical Worklist triage: Urgent cases (e.g., pneumothorax) are prioritized, supporting ED and ICU workflows.

  • Draft reporting: AI-assisted comprehensive draft reports are generated by Harrison.ai and then validated by radiologists.

AI functioned as a “second reader” from day one, highlighting subtle findings and providing immediate visual cues. This was particularly valuable in high-volume settings where small abnormalities can be overlooked.

Radiologist were initial cautious, followed by rapid acceptance once reliability was demonstrated, it improved detection of subtle findings (e.g., rib fractures, small nodules), faster clearance of normal studies, allowing focus on complex cases, leading to reduced cognitive load and reporting time.Overall, the system is now viewed as a clinical co-pilot, enhancing accuracy, prioritization, and efficiency without disrupting established workflows.

One of the big debates in healthcare right now is whether AI-assisted reporting makes radiologists sharper over time or whether it risks becoming a crutch. Now that your teams have been using this daily, what are you actually seeing?

In our experience after using Harrison’s Chest X-ray AI solution, it is clearly acting as an augmentative tool, not a crutch, when used within a strong clinical governance framework.

What we are seeing in practice are Improved detection with AI consistently helps pick up subtle findings that are easy to miss in high-volume settings, reduced cognitive load allowing radiologists to focus on complex interpretation and clinical correlation and of course more consistent reporting with reduced variability especially across shifts and centers.

Where the risk lies is with automation bias. There is a real risk if outputs are accepted without critical review and edge cases where AI can miss atypical or rare findings, so over-reliance is not acceptable.

Our operating model is that we enforce a strict human-in-the-loop approach which means AI suggests, the radiologist decides. This keeps clinical accountability intact while improving efficiency. Overall, we are seeing radiologists become sharper, not dependent. The tool enhances vigilance and consistency, but clinical judgement remains central.

Beyond the radiology reading room, one place hospitals are really struggling globally is the emergency department, with overcrowding, staffing shortages, and burnout. Can you walk us through what happens when a patient arrives in your ED with a serious chest injury and the AI is part of the process?

When a patient arrives in the Emergency Department (ED) with a serious chest injury such as suspected rib fractures, pneumothorax (collapsed lung), or hemothorax (blood in the chest) the workflow is significantly enhanced by artificial intelligence (AI), moving from subjective assessment to rapid, data-driven management. In the ED, the value of AI is speed, prioritization, and consistency under pressure.

AI could help remove delays between image acquisition and clinical actions, supporting quicker, more reliable decision-making in time-critical chest trauma cases.

All of this sounds promising from a clinical standpoint, but hospital boards want numbers. When you sit in front of your CFO and make the case for radiology AI, what is the most persuasive argument? Is it speed, accuracy, staffing efficiency, or something else?

For a CFO, the most compelling argument is capacity expansion with measurable ROI, along with accuracy. What resonates most is the ability to do more with existing manpower. AI can meaningfully boost radiologist productivity, help teams manage rising volumes. It also enables faster turnaround times (TAT), which directly improves ED throughput while driving operational efficiency through automated triage and draft reporting that reduce both reporting time and variability.

We think of AI as a throughput enabler and capacity builder, not just a diagnostic tool. The value is in increased studies reported per radiologist, faster clinical decision-making by better utilization of existing infrastructure.

Looking at the bigger picture, tuberculosis and lung cancer remain among the leading killers across South and Southeast Asia, and both are notoriously easy to miss on a chest X-ray in their early stages. With Manipal now running AI across its imaging network, are you starting to catch cases that would have previously slipped through, and could that eventually matter at a population level?

Harrison’s advanced AI technology is transforming care from a passive "wait-for-symptoms" approach to active, early detection that has the potential to alter the trajectory of these diseases at a population level. AI-assisted CXR can help surface subtle TB and lung cancer findings earlier, including cases that are easy to miss on routine reads. That matters because earlier detection can speed up confirmatory testing and treatment, which is where the real population-level impact begins.

At scale, this matters because diseases like TB are contagious, so earlier detection can help interrupt transmission chains, while lung cancer outcomes are closely linked to the stage at diagnosis, making timely identification critical. In high-burden settings, even small improvements in early detection can translate into disproportionately large public health benefits.


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